Maternal and neonatal outcomes for women with chorioamnionitis (histological or clinical)
| Outcomes | No of study | No of the patients | Effect | Certainty | ||
| ACS | Non-ACS | OR (95% CI) | Absolute (95% CI) | |||
| Maternal outcomes (histological chorioamnionitis) | ||||||
| Caesarean section | 1 | 42/97 (43.3%) | 2/12 (16.7%) | 3.82 (0.79 to 18.36) | 266 fewer per 1000 (from 30 fewer to 619 more) | Very low |
| Gestational diabetes mellitus | 1 | 6/97 (6.2%) | 2/12 (16.7%) | 0.33 (0.06 to 1.86) | 105 fewer per 1000 (from 155 fewer to 104 more) | Very low |
| Pre-eclampsia or eclampsia | 1 | 5/97 (5.2%) | 1/12 (8.3%) | 0.60 (0.06 to 5.59) | 32 fewer per 1000 (from 78 fewer to 254 more) | Very low |
| Neonatal outcomes (histological chorioamnionitis) | ||||||
| Neonatal death | 6 | 63/677 (9.3%) | 87/516 (16.9%) | 0.51 (0.31 to 0.85) | 75 fewer per 1000 (from 109 fewer to 22 fewer) | Low |
| Severe IVH | 4 | 25/414 (6.0%) | 13/114 (11.4%) | 0.41 (0.19 to 0.87) | 64 fewer per 1000 (from 90 fewer to 13 fewer) | Low |
| IVH | 5 | 42/502 (8.4%) | 26/156 (16.7%) | 0.41 (0.23 to 0.72) | 91 fewer per 1000 (from 123 fewer to 41 fewer) | Low |
| RDS | 6 | 305/677 (45.1%) | 289/516 (56.0%) | 0.59 (0.45 to 0.77) | 131 fewer per 1000 (from 196 fewer to 65 fewer) | Low |
| Sepsis | 6 | 112/677 (16.5%) | 83/516 (16.1%) | 1.03 (0.73 to 1.47) | 4 more per 1000 (from 38 fewer to 59 more) | Very low |
| Neonatal outcomes (clinical chorioamnionitis) | ||||||
| Neonatal death | 2 | 14/109 (12.8%) | 14/81 (17.3%) | 0.71 (0.32 to 1.60) | 44 fewer per 1000 (from 110 fewer to 78 more) | Very low |
| Severe IVH | 3 | 5/163 (3.1%) | 14/155 (9/0%) | 0.32 (0.03 to 3.19) | 60 fewer per 1000 (from 87 fewer to 150 more) | Very low |
| IVH | 3 | 13/163 (8.0%) | 20/155 (12.9%) | 0.43 (0.07 to 2.44) | 69 fewer per 1000 (from 119 fewer to 136 more) | Very low |
| RDS | 4 | 99/209 (47.45) | 99/208 (47.6%) | 0.74 (0.48 to 1.12) | 74 fewer per 1000 (from 172 fewer to 28 more) | Very low |
| Sepsis | 2 | 26/104 (25.0%) | 12/46 (26.1%) | 0.71 (0.13 to 3.89) | 60 fewer per 1000 (from 271 fewer to 318 more) | Very low |
There was no maternal outcome in clinical chorioamnionitis.
ACS, antenatal corticosteroid; IVH, intraventricular haemorrhage ; RDS, respiratory distress syndrome.