Baseline characteristics of 663 individuals from the Normative Aging Study and subset of 301 individuals who had more than one lung function measurement for analysis of lung function decline
| Full data set | 301 Subset | |||
|---|---|---|---|---|
| Mean (SD) or N (%) | Range | Mean (SD) or N (%) | Range | |
| Age | 72.7 (6.7) | (55.3–100.9) | 71.5 (6.4) | (55.3–91.0) |
| BMI | 28.5 (4.2) | (19.4–52.3) | 28.7 (4.1) | (20.3–52.3) |
| Pack-years* | 30.6 (24.8) | (0.1–145.5) | 28.6 (23.1) | (0.10–120.8) |
| Current smokers | 43 (7) | 23 (8) | ||
| Ever smokers | 466 (70) | 216 (70) | ||
| Folate intake† (mcg/day) | 570 (333) | (0.23–2235.17) | 617 (383) | (0.23–2001.75) |
| Alcohol intake (gm/day) | 12.0 (17.8) | (0–217.8) | 10.7 (13.8) | (0–73.5) |
| WBC (×103/mm3) | 6.7 (1.8) | (2.7–23.8) | 6.6 (2.3) | (3.2–36.6) |
| Per cent lymphocytes | 25.6 (8.0) | (5–88) | 25.0 (8.3) | (7–85) |
| Per cent neutrophils | 62.1 (8.7) | (5–85) | 62.8 (8.8) | (5–83) |
| Cardiovascular disease‡ | 115 (17) | 49 (16) | ||
| Hypertension | 280 (42) | 143 (47) | ||
| Diabetes | 75 (11) | 33 (11) | ||
| FEV1 | 2.70 (0.64) | (0.85–4.69) | 2.76 (0.62) | (1.29–4.69) |
| FEV1% predicted | 81 (17) | (28–125) | 81.8 (15.5) | (39.7–122.6) |
| FVC | 3.56 (0.72) | (1.63–6.32) | 3.64 (0.71) | (1.63–6.32) |
| FVC% predicted | 82 (14) | (43–124) | 82.6 (13.1) | (43.8–123.8) |
| FEV1/FVC | 75 (8) | (36–94) | 75.6 (7.0) | (51.6–94.4) |
| COPD | 107 (16) | 45 (15) | ||
| Alu | 26.4 (1.1) | (22.8–32.4) | 26.4 (1.10) | (22.8–32.3) |
| LINE-1 | 76.8 (1.8) | (70.1–84.6) | 77.0 (1.8) | (70.1–81.6) |
*Pack-years in current or ex-smokers only.
†Calculated based on supplement intake and fortified foods from food frequency questionnaire.
‡Angina, stroke, myocardial infarction, ischaemic heart disease.
BMI, body mass index; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; LINE-1, long-interspersed nuclear elements; WBC, white blood cell count.