Pharmacology and therapeutics

Quantitative analysis of nortriptyline’s analgesic properties: a comparative systematic review and meta-analysis
Soroush Hashemzadeh, Mohammad Mortazavi, Ramin Abdi Dezfouli

BMJ Open Aug 2024, 14 (8) e085438; DOI: 10.1136/bmjopen-2024-085438
Study protocol for ADAPT-TDM: A beta-lactam antibiotic Dose AdaPtation feasibility randomised controlled Trial using Therapeutic Drug Monitoring
Rekha Pai Mangalore, Ming Gene Chai, Jeffrey Pope, Sue J Lee, Alexander Padiglione, Arne Diehl, Llyod Roberts, Kirsty Sim, Philip Rawson-Harris, Sebastian Wicha, Hans G Schneider, Trish N Peel, Adam Jenney, Darshini Ayton, Anton Y Peleg, Andrew A Udy

BMJ Open Jun 2024, 14 (6) e083635; DOI: 10.1136/bmjopen-2023-083635
PRECISE trial (Pain RElief Combination Intervention StratEgies): protocol for the clinical trial of a pregabalin–melatonin combination for fibromyalgia
Ian Gilron, Chris DeBow, Hala Elkerdawy, James S Khan, Tim V Salomons, Scott Duggan, Dongsheng Tu, Ronald R Holden, Roumen Milev, D Norman Buckley, Dwight E Moulin

BMJ Open Jun 2024, 14 (6) e087180; DOI: 10.1136/bmjopen-2024-087180
Self-reported gastrointestinal adverse effects of non-steroidal anti-inflammatory drugs in female students with dysmenorrhoea at Makerere University: prevalence, discontinuation and associated factors. a cross sectional study
Solomon Gobba, Winnie Kibone, Ronald Kiguba

BMJ Open Jun 2024, 14 (6) e079660; DOI: 10.1136/bmjopen-2023-079660
Targeting self-care adherence for glycaemic control in multimorbid type 2 diabetes mellitus with depression using bupropion: a protocol for cross-over randomised controlled trial
Muhammad Aaqib Shamim, Ravindra Shukla, Mukesh Kumar Swami, Shival Srivastav, Anindita Pradhan, Suraj Singh Yadav, Abhishek Anil, Aswini Saravanan, Shoban Babu Varthya, Surjit Singh, Pradeep Dwivedi

BMJ Open Jun 2024, 14 (6) e077975; DOI: 10.1136/bmjopen-2023-077975
Antibiotic prescribing practice using WHO Access, Watch and Reserve classification and its determinants among outpatient prescriptions dispensed to elderly population in six community chain pharmacies in Asmara, Eritrea: a cross-sectional study
Nuru Abdu, Saleh Idrisnur, Tomas Tewelde, Eyasu H Tesfamariam

BMJ Open Jun 2024, 14 (6) e085743; DOI: 10.1136/bmjopen-2024-085743
Characterising incident opioid use among incident users of prescription sedative hypnotics: A national cohort study
James Douglas Thornton, Tyler Varisco, Harshil Patel, Mina Shrestha, Matthew Wanat, Eric Schaefer, Douglas Leslie, Hui Zhao, Randa Al Saadi, Chan Shen

BMJ Open May 2024, 14 (5) e082339; DOI: 10.1136/bmjopen-2023-082339
Development and validation of a nomogram for predicting the occurrence of renal dysfunction after treatment of immune checkpoint inhibitor: a retrospective case–control study
Jianan Su, Pengwei Chen, Yaping Yang, Ziqing Gao, Zhuofei Bi, Min Feng

BMJ Open May 2024, 14 (5) e082484; DOI: 10.1136/bmjopen-2023-082484
Low-dose naltrexone for post-COVID fatigue syndrome: a study protocol for a double-blind, randomised trial in British Columbia
Hiten Naik, Erin Cooke, Travis Boulter, Roger Dyer, Jeffrey N Bone, Melody Tsai, Jaymie Cristobal, R Jane McKay, Xiaowei Song, Luis Nacul

BMJ Open May 2024, 14 (5) e085272; DOI: 10.1136/bmjopen-2024-085272
Retrospective study investigating naloxone prescribing and cost in US Medicaid and Medicare patients
Christopher D Manko, Mohamed S Ahmed, Lavinia R Harrison, Srivastava A Kodavatiganti, Noelia Lugo, Jason Osei Konadu, Farrin Khan, Carrie A Massari, Tenisha K Sealey, Maame Efua Addison, Celine N Mbah, Kenneth L McCall, Joseph B Fraiman, Brian J Piper

BMJ Open May 2024, 14 (5) e078592; DOI: 10.1136/bmjopen-2023-078592

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