Gastrointestinal tumours

Evaluation of tyrosine kinase inhibitors combined with antiprogrammed cell death protein 1 antibody in tyrosine kinase inhibitor-responsive patients with microsatellite stable/proficient mismatch repair metastatic colorectal adenocarcinoma: protocol for open-label, single-arm trial
Qian Dong, Yanwen Diao, Xin Sun, Yang Zhou, Jialing Ran, Jingdong Zhang

BMJ Open Apr 2022, 12 (4) e049992; DOI: 10.1136/bmjopen-2021-049992
Laparoscopic versus open pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: study protocol for a multicentre randomised controlled trial
Shutao Pan, Tingting Qin, Taoyuan Yin, Xianjun Yu, Jing Li, Jun Liu, Wenxing Zhao, Xuemin Chen, Dewei Li, Jianhua Liu, Jingdong Li, Yahui Liu, Feng Zhu, Min Wang, Hang Zhang, Renyi Qin

BMJ Open Apr 2022, 12 (4) e057128; DOI: 10.1136/bmjopen-2021-057128
Undifferentiated-predominant mixed-type early gastric cancer is more aggressive than pure undifferentiated type: a systematic review and meta-analysis
Peng Yang, Xiang-Dong Zheng, Jun-Mei Wang, Wen-Bin Geng, Xiaoyong Wang

BMJ Open Apr 2022, 12 (4) e054473; DOI: 10.1136/bmjopen-2021-054473
Postoperative survival of extrahepatic and intrahepatic cholangiocarcinoma after surgery: a population-based cohort
Wei-Wen Liu, Jian-Fei Tu, Xi-Hui Ying, Zheng-Ju Chen, Yun-Bing Wang

BMJ Open Apr 2022, 12 (4) e049789; DOI: 10.1136/bmjopen-2021-049789
Electroacupuncture versus sham electroacupuncture in the treatment of postoperative ileus after laparoscopic surgery for colorectal cancer: study protocol for a multicentre, randomised, sham-controlled trial
Xuan Zou, Ying-Chi Yang, Yu Wang, Wei Pei, Jia-Gang Han, Yun Lu, Mao-Shen Zhang, Jian Feng Tu, Lu Lu Lin, Li-Qiong Wang, Guangxia Shi, Shi-Yan Yan, Jing-Wen Yang, Cun-Zhi Liu

BMJ Open Apr 2022, 12 (4) e050000; DOI: 10.1136/bmjopen-2021-050000
Effect of different oesophagojejunostomy methods on the quality of life of gastric cancer patients after totally laparoscopic total gastrectomy with self-pulling and latter transected technique: study protocol for a randomised trial
Jian Wang, Yujen Tseng, Jun Hong, Lu-Chun Hua, Ya-Ping Wang, Han-Kun Hao

BMJ Open Apr 2022, 12 (4) e058844; DOI: 10.1136/bmjopen-2021-058844
AVOID; a phase III, randomised controlled trial using indocyanine green for the prevention of anastomotic leakage in colorectal surgery
Ruben P J Meijer, Robin A Faber, Okker D Bijlstra, Jeffrey P B M Braak, Elma Meershoek-Klein Kranenbarg, Hein Putter, J Sven D Mieog, Koos Burggraaf, Alexander L Vahrmeijer, Denise E Hilling

BMJ Open Apr 2022, 12 (4) e051144; DOI: 10.1136/bmjopen-2021-051144
Patient-reported experiences and views on the Cytosponge test: a mixed-methods analysis from the BEST3 trial
Roberta Maroni, Jessica Barnes, Judith Offman, Fiona Scheibl, Samuel G Smith, Irene Debiram-Beecham, Jo Waller, Peter Sasieni, Rebecca C Fitzgerald, Greg Rubin, BEST3 Consortium, Fiona M Walter

BMJ Open Apr 2022, 12 (4) e054258; DOI: 10.1136/bmjopen-2021-054258
Gastric cancer completeness in Finnish Cancer Registry and Finnish Patient Registry: a population-based nationwide retrospective cohort study
Urgena Maharjan, Joonas H Kauppila

BMJ Open Apr 2022, 12 (4) e056320; DOI: 10.1136/bmjopen-2021-056320
Effect of partial preservation versus complete preservation of Denonvilliers’ fascia on postoperative urogenital function in male patients with low rectal cancer (PREDICTION): protocol of a multicentre, prospective, randomised controlled clinical trial
Zhifang Zheng, Daoxiong Ye, Xiaojie Wang, Xingrong Lu, Ying Huang, Pan Chi

BMJ Open Apr 2022, 12 (4) e055355; DOI: 10.1136/bmjopen-2021-055355

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